Cyclopropanecarboxylic acids and derivatives
Medchemexpress LLC VH032-cyclopropane-F | 2306193-99-5 | MFCD32201089 | 99.9% | 532.63 | C26H33FN4O5S | 5MG
VH032-cyclopropane-F is a VH032-based von Hippel-Lindau (VHL) E3 ligase ligand used as the VHL-recruiting moiety in targeted protein degradation research (PROTACs). It is supplied as a solid research reagent with characterized physical and chemical properties and is designed for use in synthesis and biochemical assay development.
- High purity reported (99.92%) for research applications.
- Available in multiple small-scale pack sizes for synthesis and testing.
- Stable as a powder at -20°C and in solvent under recommended storage conditions.
- Molecular weight 532.63 and formula C26H33FN4O5S for unambiguous identification.
- Intended for use as a VHL-recruiting building block in degrader design.
Medchemexpress LLC Vh032-cyclopropane-F | 2306193-99-5 | MFCD32201089 | ≥95.0% | 532.63 | C26H33FN4O5S | 10MG
VH032-cyclopropane-F is a VH032-based von Hippel-Lindau (VHL) ligand used as an E3 ligase recruiter in PROTAC design and synthesis. The compound contains a functionalized cyclopropane terminus that facilitates conjugation to target ligands via linkers, enabling construction of bifunctional degraders and in vitro evaluation of VHL-mediated activity.
- Used as an E3 ligase (VHL) ligand for PROTAC design and synthesis.
- Molecular formula C26H33FN4O5S; molecular weight 532.63.
- CAS number 2306193-99-5 for compound identification.
- Soluble in DMSO at 100 mg/mL (requires ultrasonic) and formulatable for in vivo at ≥2.5 mg/mL in common vehicle systems.
- Storage: powder at -20°C; in solvent at -80°C (6 months) or -20°C (1 month).
- Purity typically ≥95% (supplier dependent).
- Supplied in small research quantities such as 10 mg vials for synthetic applications.
eMolecules Key Organics/BIONET Cyclopropane methanol 20mg 629237943 STR04478 90 000 2516-33-8 MFCD00001309 72 107 C4H8O
Key Organics/BIONET Cyclopropane methanol 20mg 629237943 STR04478 90 000 2516-33-8 MFCD00001309 72 107 C4H8O
Accela Chembio Inc 1-(cyclopropylcarbonyl)piperazine | 5g | 59878-57-8 | MFCD06369645 | 97% | D: 1.087 | Shelf Life: 1260 Days | Light Sensitive/nitrogen Or Argon
1-(cyclopropylcarbonyl)piperazine | 5g | 59878-57-8 | MFCD06369645 | 97% | D: 1.087 | Shelf Life: 1260 Days | Light Sensitive/nitrogen Or Argon
eMolecules Oakwood Chemical Cyclopropanecarbonyl chloride 2 5kg 825883166 066721 0 000 4023-34-1 MFCD00001277 104 530 C4H5ClO
Oakwood Chemical Cyclopropanecarbonyl chloride 2 5kg 825883166 066721 0 000 4023-34-1 MFCD00001277 104 530 C4H5ClO
eMolecules Key Organics/BIONET Cyclopropane methanol 10mg 564353493 STR04478 90 000 2516-33-8 MFCD00001309 72 107 C4H8O
Key Organics/BIONET Cyclopropane methanol 10mg 564353493 STR04478 90 000 2516-33-8 MFCD00001309 72 107 C4H8O
eMolecules (1-Methoxymethyl-cyclopropyl)-methyl-amine hydrochloride | 1255717-61-3 | MFCD18071229 | 5g
J & W PharmLab LLC | (1-Methoxymethyl-cyclopropyl)-methyl-amine hydrochloride | 5g | 415670605 | 20R0824S | 98.000 | 1255717-61-3 | MFCD18071229 | 151.630 | C6H14ClNO
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Medchemexpress LLC VH032-cyclopropane-F | 2306193-99-5 | MFCD32201089 | >95.0% | 532.63 | C26H33FN4O5S | 10MM 1ML
VH032-cyclopropane-F is a VHL E3 ligase ligand used as a building block for PROTAC design and for ligand-E3 ligase binding studies. It is supplied as a 10 mM solution in DMSO (1 mL) and as a solid powder, enabling direct use in assay development or conjugation chemistry.
- Provided as 10 mM solution in DMSO (1 mL) and as powder.
- Molecular weight 532.63.
- Chemical formula C26H33FN4O5S.
- Purity ≥95%.
- Storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Intended for use in PROTAC construction and E3 ligase binding studies.
eMolecules Key Organics/BIONET Cyclopropane methanol 25mg 629237935 STR04478 90 000 2516-33-8 MFCD00001309 72 107 C4H8O
Key Organics/BIONET Cyclopropane methanol 25mg 629237935 STR04478 90 000 2516-33-8 MFCD00001309 72 107 C4H8O
eMolecules Pharmablock ethyl cyclopropanecarboxylate 100mg 551332958 PBTF557 0 000 4606-07-9 MFCD00001282 114 144 C6H10O2
Pharmablock ethyl cyclopropanecarboxylate 100mg 551332958 PBTF557 0 000 4606-07-9 MFCD00001282 114 144 C6H10O2
Medchemexpress LLC Vh032-cyclopropane-f | 2306193-99-5 | MFCD32201089 | >95.0% | 532.63 g/mol | C26H33FN4O5S | 100MG
VH032-cyclopropane-F is a VH032-based ligand for the von Hippel-Lindau (VHL) E3 ubiquitin ligase used as a building block in PROTAC and E3 ligase research. The compound has molecular formula C26H33FN4O5S, molecular weight 532.63 g/mol, and CAS 2306193-99-5. It is provided as a research-grade small molecule; handle according to applicable safety data and laboratory practices.
- VHL E3 ligase ligand suitable for PROTAC assembly.
- Molecular formula C26H33FN4O5S and Mw 532.63 g/mol.
- High purity (≥95.0%) appropriate for biochemical studies.
- Solid material for dissolution in common organic solvents.
- Intended for research use only; not for human or veterinary use.
eMolecules Key Organics/BIONET Cyclopropane methanol 50mg 564353494 STR04478 90 000 2516-33-8 MFCD00001309 72 107 C4H8O
Key Organics/BIONET Cyclopropane methanol 50mg 564353494 STR04478 90 000 2516-33-8 MFCD00001309 72 107 C4H8O
Medchemexpress LLC Vh032-cyclopropane-f | 2306193-99-5 | MFCD32201089 | ≥95.0% | 532.63 | C26H33FN4O5S | 50MG
VH032-cyclopropane-F is a von Hippel-Lindau (VHL) E3 ligase ligand used as a building block for PROTACs and targeted protein degradation. It features a hydroxyl-functionalized site for linker attachment and is formulated for both in vitro and in vivo studies.
- VHL E3 ligase ligand suitable for PROTAC design and conjugation.
- Hydroxyl-functionalized site for linker attachment.
- Soluble in DMSO at 100 mg/mL (187.75 mM; may require sonication) for in vitro use.
- Formulatable for in vivo dosing at ≥2.5 mg/mL in common vehicles.
- Powder stable at -20°C for long-term storage; solutions stable at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC 4-hydroperoxycyclophosphamide | 39800-16-3 | MFCD01710226 | >98.0% | 293.08 g/mol | C7H15Cl2N2O4P | 50 MG
4-hydroperoxycyclophosphamide is the activated hydroperoxide metabolite of cyclophosphamide used as a research reagent to study DNA cross-linking, apoptosis, and reactive oxygen species (ROS)-mediated mitochondrial death pathways. It is supplied for research use only and not for human or clinical use.
- Activated metabolite that cross-links DNA and induces T cell apoptosis.
- Useful for in vitro studies of apoptosis, oxidative stress, and DNA damage.
- High solubility in DMSO (50 mg/mL); ultrasonic agitation recommended for dissolution.
- Storage guidance: store at -20°C under inert gas; in solution store at -80°C up to 6 months, or -20°C up to 1 month under nitrogen.
- Molecular weight 293.08 g/mol; formula C7H15Cl2N2O4P.
- For research use only; not intended for human or clinical applications.
eMolecules 2-(2-Bromophenyl)cyclopropane-1-carboxylic acid | 767359-25-1 | MFCD12068266 | 1g
Combi-Blocks | 2-(2-Bromophenyl)cyclopropane-1-carboxylic acid | 1g | 415501016 | QM-9800 | 98.000 | 767359-25-1 | MFCD12068266 | 241.084 | C10H9BrO2
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